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Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial

The genes included those encoding enzymes associated with the cell wall synthesis ( BCIN_12g06300, BCIN_05g01660 , and BCIN_06g03790 ), ABC transporters ( BCIN_01g03740 , and BcatrA ), ER stress ( Bcsec62, Bcufd2 , and Bcire1 ), and peroxisomal ( Bccat5 , and BccatA ), as well as some resistance genes ( Bcgst1, BCIN_09g02790, BCIN_02g07440, Bcpie2 , and BCIN_01g09530 )

For instance, the influenza HA glycoprotein is a homotrimer in which each monomer consists in two-disulfide linked subunits

Further to this finding, being involved in trials with vitamin C did not show any significant changes in bio-oxidative indicators or pharmacodynamics endpoints (20)

Exploring additional biomarkers will likely become a key focus in future clinical trials to accurately select patients with low risk of local recurrence and further stratify these already low-risk individuals