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For the negative control, the denatured recombinant protein boiled for 7 min was used as the substrate

Leu can bind to Sestrin2 (a negative regulator of mTORC1 activity) to promote mTORC1 activation, 46 thereby promoting protein synthesis in the liver and other tissues

Research shows tesofensine differentially modulates neuronal ensembles and population activity in the lateral hypothalamus, with greater weight loss effects observed in obese rats compared to lean rats

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This balance provides a crucial indicator of cellular health and resilience against oxidative stress