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The need for homeostatic mechanisms to counteract these negative effects of Hebbian learning rules has been recognized since the earliest computational work on the subject (Von der Malsburg, 1973) and validated and specified in further work demonstrating that, to achieve both learning and stability of operation, neuronal networks need to be equipped with mechanisms of synaptic plasticity additional to Hebbain-type rules (e.g., Miller and MacKay, 1994

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95 % CI (-095, 117), P = 0839) (online Supplementary Fig