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Unlike GHRH, GHS was only weakly effective in vitro when incubated with pituitary tissue

Comparator Selection: Full-length hGH (to demonstrate receptor-independent effects) -adrenergic agonists (to show distinct mechanism) Vehicle control 4

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Constipation Occurs due to slowed gastric emptying and reduced food intake

Methods Enzymol 454:367404 [DOI] [PMC free article] [PubMed] [Google Scholar] Borkan GA, Gerzof SG, Robbins AH, Hults DE, Silbert CK, Silbert JE 1982 Assessment of abdominal fat content by computed tomography