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The metabolic cycle in which B vitamins, including B12, interact with enzymes in the body is quite complicated

Published preclinical data in rodents suggests doses equivalent to 200mg+ in humans produce off-target effects on folate metabolism and S-adenosylmethionine (SAMe) pools

How it works: Melanotan II activates melanocortin receptors that stimulate melanin production in your skin (the pigment that causes tanning)

Handling and use of these products should be restricted to suitably qualified professionals

What is B12 needed for

Vegans, vegetarians, and people with restrictive diets may not consume enough B12, making ongoing injections valuable