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The cv showed a slope of 4.95 A M 1 , corresponding to an area-normalized sensitivity of 99 A M 1 cm 2 , with excellent linearity (R 2 = 0.99) and a LOD of 4.29 M, indicating that cv is most suitable for mechanistic investigations rather than trace-level detection

Absorption of oral glutathione can be affected by stomach acid or enzymes in the duodenum, which can break glutathione into its amino acid components

The IV studies tend to show faster and more pronounced results at the higher achievable concentrations

Sighs are reported to result from activation of a neuronal circuit in the preBtzinger complex/parafacial group 133 while apnea results from direct inhibition of the preBtzinger complex or inhibition of drive to phase-switching neurons in the preBtzinger complex 134

In human research of chronic insomniacs DSIP had normalizing influence on sleep regulation

& Winther, J