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After treatment, cells were maintained in GM for 23 days before analysis

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Conducting in-depth mechanistic studies using models such as nonhuman primates that can truly simulate human pathological processes would be crucial

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In research, Melatonin is studied for its potential effects on sleep regulation, antioxidant activity, immune modulation, and neuroprotection

This design choice introduces potential bias, particularly for subjective outcomes, but it reflects the practical reality that these treatments have different injection devices and titration schedules that would make blinding extremely difficult