PMID 12086680
Investigations are guided by clinical suspicion rather than routine panels: for example, thyroid function tests and ferritin may be checked if symptoms suggest deficiency or thyroid disease, while an androgen profile may be appropriate in women presenting with menstrual irregularity, hirsutism, or acne
The first is extracellular matrix biology: fibroblast culture and rat wound-chamber work from the Maquart and Simeon groups reported that GHK-Cu stimulates collagen, glycosaminoglycan and small proteoglycan synthesis while simultaneously upregulating matrix metalloproteinase-2 and its tissue inhibitors, a combined synthesis-and-turnover signature unusual among matrix-active compounds
As magnesium is depleted, the parasympathetic nervous systemthe "rest and digest" branch responsible for calming the body downloses its primary chemical braking mechanism
To summarize, mounting evidence suggests that S- glutathionylation plays an important role in the regulation of several primary metabolism enzymes, and could impact carbon metabolism during conditions inducing oxidative stress
It is thought that low glutathione contributes to the development of many conditions and also worsens the illness and inhibits recovery
