Vit B12 only occurs in animal products and vegans have to take supplements
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"LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: from discovery to clinical proof of concept." Cell Metabolism
Specifically, NET-associated elastase degrades VE-cadherin at intercellular junctions, increasing vascular permeability and leakage (278)
There are little to no risks associated when used as a supplement by people with low to normal red blood cell levels
Nature 459 , 262265 (2009)