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The FDA has issued specific warnings about compounded GLP-1 medications: No efficacy review: Compounded versions haven't been tested in clinical trials to prove they work No manufacturing inspection: Compounding pharmacies aren't held to the same standards as pharmaceutical manufacturers Salt form concerns: FDA has warned against using certain salt forms to compound tirzepatide Compounded tirzepatide safety risks you should know Safety concerns about compounded tirzepatide are legitimate and worth understanding before making any decisions

The researchers studying semaglutide used 1 mg doses