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But the class of drugs Ozempic belongs to would change this and generate A$21 billion of sales in 2023 alone for its maker

Cardiovascular outcome trials have established benefits for specific agents: the LEADER trial for liraglutide, SUSTAIN-6 for injectable semaglutide, and REWIND for dulaglutide demonstrated reduced risk of major adverse cardiovascular events in patients with type 2 diabetes

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Am J Pathol 1998

Science 325 , 10811082 (2009)

But neither of these mechanisms involves GLP-1 receptors, incretin hormones, or any of the pathways that GLP-1 receptor agonists target