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PMID 21668043

What is supported in animal models Increased lipolysis, increased fat oxidation, decreased lipogenesis, no apparent effect on plasma glucose or insulin sensitivity, and signal that intact beta-3 adrenergic receptor activity matters for the fat-loss effect

More advanced disease may present with wet beriberi (dilated cardiomyopathy resulting in high-output heart failure and pulmonary edema) or Wernicke-Korsakoff syndrome, which is a combination of Wernicke encephalopathy (characterized by the triad of confusion, ataxia, and ophthalmoplegia) and Korsakoff syndrome (amnesia and confabulation)

This is called protracted withdrawal

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A significant decrease in arachidonate levels (20:4n-6) may be the cause of anti-inflammatory effects