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29 (2 Suppl): S38S51

Strengthen the skin barrier: Topical probiotic skin care has the potential to strengthen the barrier, which lowers irritation

It is non-toxic at topical concentrations and shows no evidence of irritation in human studies 6

the 9 December 2026 NICE PCOS guideline GID-NG10436

However, study shows that it can lighten skin tone by reducing the production of dark melanin in the skin and promotes creation of lighter pigments

This includes: Using a sterile needle and syringe Inserting the needle at a 90-degree angle to the skin Aspirating to check for blood return before injecting Injecting slowly to minimize discomfort By following these steps, the Vitamin B12 goes into the muscle tissue effectively