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Guo L, Yang W, Dong X, et al

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The Weight Regain Evidence Most patients regain 5070% of lost weight within 12 months of stopping without a structured maintenance plan Hunger and cravings typically return to pre-treatment levels within 24 weeks of stopping Metabolic improvements (blood sugar, blood pressure, lipids) also partially reverse after stopping Patients who built strong protein and exercise habits during treatment maintain significantly more of their weight loss 6

In addition, treatment with VK2735 led to mean weight loss of up to 18 pounds from baseline