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If any unusual symptoms arise, discontinue use and consult a healthcare professional for guidance

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(146) observed significant blood-to-brain influx for non-acylated GLP-1 mimetics like exendin-4 and lixisenatide, whereas acylated GLP-1 analogues such as liraglutide and semaglutide showed minimal blood-brain barrier penetration in mice

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Non-diabetic patients in these trials experienced benefits beyond weight reduction, including improved cardiovascular markers, better blood pressure control, and reduced inflammation