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As a result, the drug was eventually approved for treating obesity

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: the PIONEER 3 Randomized Clinical Trial

Step-I: Selective cleavage of resin from protected peptide resin obtained from step-H was performed with tert-butyl amine (35.1 grams) in n-heptane

Martinelli D, Diodato D, Ponzi E, Monn M, Boenzi S, Bertini E, Fiermonte G, Dionisi-Vici C (2015) The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome