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doi:10.1007/s10815-025-03720-1

10.1016/j.ecoenv.2023.115000 77 ChenY.BaiJ.WuD.YuS.QiangX.BaiH.et al

On the contrary, inhibition of cholesterol storage results in suppressed tumor growth of mouse prostate cancer xenografts [53], while pharmacologic disruption of PI3K-SREBP-dependent LDLR activation induces glioblastoma tumor cell death [32]

Statements Author contributions DS, RC, and CRM contributed equally to the paper and help with writing and figures

These results, together with known structures and functional data for other SRCR domains, inform generally on ligand recognition by proteins in the SRCR-SF