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The pathway analysis using KEGG on GH Treatment Responsive Biomarkers in male mice revealed several significantly impacted metabolic pathways, as illustrated in Figure 7 and detailed in Table 3

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This hormone plays a crucial role in regulating blood sugar, insulin secretion, and appetite

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Both non-enzymatic and enzymatic reaction products of MBB, in presence of GSH in phosphate buffer (pH 6.5), were measured by following increase of fluorescence at wavelength of 475nm

Seven of the 19 XChem hits were shown to bind to the protein, but with only a modest average peak intensity reduction of 2037% in the CPMG assay (Supplementary Table 2), suggesting that the fragments likely bound with weak (millimolar) affinities, at the very limit of the CPMG assay sensitivity