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[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

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On top of that, any NAD+ that your cells do have left gets used up faster in response to stress, illness, or environmental damage

Your GP or endocrinologist can help differentiate between expected physiological adjustments and symptoms requiring intervention

It helps maintain bone density, enhances immunity, manages underactive parathyroid, and prevents rickets