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Both animal [76] and human [77] studies suggest that VPA-induced hyperammonaemia may be enhanced via renal rather than hepatic mechanisms

Therefore, loss of the integrity of melanosome membranes with leakage of these intrinsic toxic agents has the potential to cause self-injury to the melanocytes [6]

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"The big strategic concept here is that a qualified medical expense that is incurred any time after the HSA has been opened can be reimbursed at the time of service or any time thereafter," says Malcolm