In fact, the only study that I could find involving humans was a very small retrospective study with just 16 participants
ACG Case Rep
FROM THE ANALYST'S COUCH By Gideon Heap 1 & Graeme Green 2 Carles Recasens-Alvarez Clarivate, Barcelona, Spain
Nature 379 , 6972 (1996)
To overcome these limitations, this review discusses a range of structural modifications, including N-terminal and C-terminal substitutions, fatty acid conjugation, and large molecule fusion technologies, which have collectively contributed to enhanced half-life, increased stability, improved receptor affinity, and retained or augmented bioactivity of GLP-1 analogs
An open-label, single-center proof of concept study evaluating the efficacy and safety of tirzepatide for moderate to severe hidradenitis suppurativa