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2 Transporter-Mediated DDIs Efflux transporters (P-gp, BCRP) Uptake transporters (OATP, OCT) Example: P-gp inhibition increasing digoxin exposure
Animal studies found an increased risk for colorectal cancer, although that risk hasn't been shown in humans
Givens, D., & Barber, W
Understanding the structure and function of the skin
Methods Overexpression and purification of recombinant proteins The coding regions of ShD14 (GenBank: KR013120.1), ShHTL1 (GenBank: KR013121.1), ShHTL4 (GenBank: KR013124.1), and ShHTL7 (GenBank: KR013127.1) were amplified by reverse transcription PCR, using the total RNA of S
10.3390/ijms20133316 57 GiordanoT
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