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Creating a Salt and Ice Water Mixture Your bucket or cooler should be large enough to hold both bottles of water without them touching each other

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Evidence suggests MRS is inadequate, however, and often yields inconsistent results across studies

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Crit Rev Food Sci Nutr 58(15):25832597

[1] However, because B12 is water-soluble, the body typically eliminates excess amounts through renal excretion without adverse effects