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Talk to your doctor about over-the-counter anti-diarrheal, laxatives, or anti-nausea medications, depending on what side effects youre experiencing

to estimate insulin sensitivity in patients treated with placebo, TZP or semaglutide after 28 weeks of treatment, achieving a hyperinsulinemic, euglycemic clamp experiment, followed by a hyperglycemic clamp (216 mg/dL) to estimate insulin secretory responses

At Revive MD, our board-certified endocrinologist, Dr

Safety and Clinical Considerations Gastrointestinal adverse effects The most common adverse effects of incretin-based therapies are gastrointestinal, including nausea, vomiting, diarrhea, constipation, dyspepsia, and abdominal discomfort

Despite these side effects, the overall incidence of adverse events leading to discontinuation of treatment was relatively low

In clinical trials, however, preclinical cardiovascular benefits were not sustained, and increased hospitalizations for HF and fractures were observed