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Notably, FOXO4-DRI treatment did not cause significant changes in body weight or testis weight, suggesting a targeted effect [1]

While BPC-157 does not develop traditional tolerance since it operates non-hormonally and does not suppress natural production, the possibility of receptor desensitization remains a theoretical concern

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Eligible patients who completed the screening period entered the lead-in treatment period, which included 16 weeks of open-label metformin HCl and 10 mg dapagliflozin treatment