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Transgenic female mice treated with intranasal GHK-Cu had higher alternation percentages in the Y maze, indicating improved cognitive performance, beginning as early as the second month of treatment (Week 8), and continuing through the third month (Week 12) when the study ended, compared to transgenic mice treated with intranasal saline (Figure 1A)

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The ferroptosis inhibitor ferrostatin-1 (fer-1) and another antioxidant, the water-soluble vitamin E analogue Trolox, prevent a decrease in viability