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By comparison, orlistat (Xenical) produced approximately 3-4 kg more weight loss than placebo over 12 weeks in its pivotal trials, and GLP-1 agonists produce 8-15 kg more than placebo
Biochem J
It is not FDA-approved for general weight loss, but can be used off-label in personalized medicine settings under provider supervision
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I need to drop 15-20 pounds. Mar 26, 2026 My favorite family
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