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Orforglipron's structural features, derived from the Chugai-discovered OWL833 series, appear to confer a favorable metabolic and toxicological profile that was not shared by the Pfizer compounds

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Interesting thought SULFUR AND HEAVY METALS Sulfate is also very important in the clearance of heavy metals

Moreover, the combined GLP-1 mechanisms of weight loss and delayed carbohydrate absorption may also be the key drivers of remission of type 2 diabetes and reduced cardiovascular events found by GLP-1 analogues