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Retatrutide: A Triple Threat in Metabolic Regulation Retatrutide stands as a cutting-edge pharmaceutical peptide, developed by Eli Lilly, designed to address the complex challenges of obesity and type 2 diabetes

doi:10.2337/dc20-1473

Phase 2 trials showed 17.5% weight loss at 24 weeks and 24.2% at 48 weeks at the 12mg dose

Its also worth repeating here that most GLP-1 side effects occur within the first week or two of beginning the weight loss medication and are usually mild to moderate, decreasing within the first two months

doi: 10.1177/26345161251353437 Kato S, Sato T, Fujita H, Kawatani M, Yamada Y

Gastrin is a neuroendocrine peptide, which acts on the cholecystokinin-2 (CCK2) receptor and is expressed in the pancreas with the rationale being that as it is involved in pancreas development, it might increase -cell mass and glycemic control [70]