doi: 10.1016/S0140-6736(21)01324-6 223 CefaluWTKaulSGersteinHCHolmanRRZinmanBSkylerJSet al
Before you blame your age, your kids, or your overflowing to-do list, consider something surprisingly common: dehydration
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The oxidation-generated reducing equivalents accumulate as cytosolic NADPH produced by the pentose phosphate pathway, and mitochondrial NADH, produced by 2-oxo acid dehydrogenases
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Compound structure is represented by tethered triangles and a cycle.(B) Workflow for detecting membrane targets of BRD4-VHL-biotin.(C) Structures of trivalent PROTACs SIM1 and SIM1-Me