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What research has explored: Published studies in journals including Metabolism and the Journal of Ethnopharmacology have examined berberine in the context of glucose metabolism, insulin sensitivity, and metabolic signaling pathways

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This represents favorable tolerability relative to efficacy

A nationwide register-based cohort and self-controlled case series study

The most common side effects include nausea, vomiting, diarrhea, and constipation particularly during initiation and dose escalation

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