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Notably, focal adhesion kinase (FAK), a key signaling protein within FAs, is activated through integrin engagement with the ECM, resulting in autophosphorylation and activation of downstream signaling pathways like MAPK/ERK (Paszek et al, 2005)

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ASP-BBR-PM@HNK and free HNK release curves at different GSH concentrations are shown in Fig

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The presence of the antioxidant GPX4 has also been shown to neutralize the ROS produced by the oxidative stress of AT and control AT inflammation by preventing lipid peroxidation (43)

[168] While short-term use for specific situations like jet lag is well-established, the safety and efficacy of long-term melatonin supplementation remain areas of ongoing research