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GLP-1 medications are typically used as a long-term treatment for weight management

Pendulum itself states that meaningful microbiome changes require approximately 90 days

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Statements Author contributions J-YW and Q-WW wrote the first draft of the manuscript

10-13 In subsequent trials where higher doses of the GLP-1/GIP agonists were used in non-diabetic obese subjects, weight loss of 15% to 21% of body weight was seen

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