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J Toxicol Environ Health B Crit Rev

Oxidative stress is associated with diseases such as cardiovascular disease, Alzheimer's disease, multiple sclerosis (MS), Parkinson's disease and cancer, and is also thought to play a major role in aging, as the body becomes less efficient as repairing cellular damage

Q.et al (2011)

This deficiency can lead to a variety of symptoms, including neurological problems, liver dysfunction, and hemolytic anemia

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The ALDH4A1 gene is located on chromosome 1p36.13 and is composed of 16 exons that generate four alternatively spliced mRNAs, two of which encode the same protein