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SDF-1 may also play a critical role in the genesis of retinopathy, which starts with damage to small blood vessels in the eye but whose progression depends on a neovascular response that can be exacerbated by SDF-1 [18, 25]

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In the OASIS 4 clinical trial, 307 adults with obesity or overweight and at least one weight-related condition, such as hypertension or hyperlipidemia, participated in the study