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Additionally, these cells showed upregulation of the synthesis of ser/gly synthesis-derived nucleotides, as indicated by the enrichment of m + 6 isotopologues, i.e., AMP in 1919 PSPH amp cells, CTP in 1919 PSPH V116I cells and GTP in both cell models, compared to 1919 control cells (Fig

Thus, nanosystems are likely to enhance the therapeutic efficacy of melanoma drugs

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