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Eli Lilly has indicated an NDA filing in Q4 2026 at the earliest, which realistically puts an FDA decision in 2027 or later

Comment: Multiple commenters supported our continued use of the hospital market basket as the annual update mechanism for ASC payments through CY 2026, with several organizations noting that this policy helps align cost and resource calculations between hospital outpatient departments and ambulatory surgery centers and supports migration of services to lower-cost settings

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Science 353(6307):1514

Currently, FOXO4-DRI is being investigated for its role in studies involving cellular senescence, transcription factor regulation, DNA damage response signaling, and aging-related cellular models