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Many report no serious issues

Because it is classified as a neuromodulating nonapeptide, it crosses the blood-brain barrier under specific laboratory observation conditions

Chronic hypoxia promotes -syn phosphorylation at ser129 and abnormal aggregation in the mouse hippocampus Hyperphosphorylation and abnormal aggregation of -syn are closely related to neuronal degeneration

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If sterile water is used, it should be used within 24 hours due to the risk of bacterial growth