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By activating GIP receptors, tirzepatide enhances insulin secretion in a glucose-dependent manner, meaning it stimulates insulin release only when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia

[DOI] [PubMed] [Google Scholar] 55.Liu ZX, Kaplowitz N

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The novel Glp-1/Gip dual receptor agonist Da3-Ch is neuroprotective in the pilocarpine-induced epileptogenesis rat model

Malhotra A, et al