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5A), with a 10% drop in body weight for the highest dose, and an 8% reduction with the 10 and 5 nmol/kg doses relative to vehicle-treated PWA mice (Fig

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3 Gastrointestinal hormone secretion The GBA is a bidirectional communication system formed by the CNS and the gastrointestinal tract, involving humoral pathways (gut-brain peptides, gut microbial metabolites, and cytokines) and neural pathways mediated by the vagus, spinal nerve, and the autonomic nervous system

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