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Gundem, G

d , Immunofluorescence analysis of indicated proteins in HeLa cells treated with vehicle or BSO (1 mM) for 24 h

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Activated AMPK regulates A metabolism through two pathways: 1) Inhibiting the NF-B signaling pathway reduces transcriptional regulation of -secretase (BACE1), thereby decreasing BACE1 enzyme production and its mediation of amyloid precursor protein (APP) cleavage and A generation (Figure 2)

Bray GP, Mowat C, Muir DF, Tredger JM, Williams R

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