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Staying hydrated, avoiding frequent snacking, and giving your body enough time to adjust to each dose also play an important role

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Given the high prevalence of obesity, this will incur a substantial economic cost to be borne either by the patient or the state

Retrieved 27 October 2019

After a 6-week lead-in period, patients who received single-blind sibutramine had on average a 2.2 kg reduction of body weight, a 2.0 cm reduction of waist circumference, a 3.0 mm Hg decrease in systolic blood pressure, a 1.0 mm Hg decrease in diastolic blood pressure, and a 1.5 mm Hg decrease in pulse rate