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227 Determining whether GLP-1 has direct/indirect effects on islet alpha-cells and what receptor(s) mediate these actions requires further investigation

Pacing is not about reacting to fatigue once it arrives, but about managing effort now based on its future consequences

Data from a large, randomized clinical trial named SELECT indicate cardiovascular protective benefits from taking the GLP-1 weight loss therapeutic Wegovy (semaglutide) for a sub-population with preexisting cardiovascular disease

The compound has a half-life of approximately six days, which allows for convenient once-weekly dosing

PMID: 33479187

Y., Kim, S