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Laboratory studies use 5mg, 10mg, and 15mg doses to investigate dose-dependent effects, with the peptides stability allowing precise observation of slow signaling pathways

The drug can cross the blood-brain barrier (BBB) and activate GLP-1R in the CNS [49, 50], thus producing neuroprotective and anti-inflammatory effects [50,51,52,53,54,55]

By influencing these neurotransmitters, peptide DSIP can promote slow-wave sleep, regulate sleep-wake cycles, and modulate stress responses

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They also assume that the effects from the trials which were on adults with obesity, type 2 diabetes, or established cardiovascular or kidney disease also apply to healthier adults