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Epigenetic modifications, such as DNA methylation and chromatin remodeling, also play critical roles in regulating NRF2 expression and function

To further analyze the effect of 3-MA on vitiligo fibroblast growth, parallel immunofluorescence analysis employing the proliferation marker Ki67 demonstrated a decrease in percentage of cycling fibroblasts after 3-MA, which appeared significant at 48 h of treatment

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