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The balance between NAD+ biosynthesis and consumption in ageing

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In contrast to initial reports placing GSH synthesis to both plastids and cytoplasm, the first enzyme of the pathway, -glutamylcysteine synthetase, is strictly localized in plastids, at least in Arabidopsis (Wachter et al., 2005)

12 Newman LJ, Lopez R, Cole HS, Boria MC, Cooperman JM