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Die Akd hat vor dem Hintergrund der Fallmeldungen zu Ketoazidosen Empfehlungen gegeben, wie diese Risiken gemindert werden knnen (siehe unten)

(2) intravenous administration of sodium bicarbonate to counteract metabolic acidosis, increase the ionization of salicylate in the kidneys, and thereby enhance the rate of excretion of salicylate

[DOI] [PMC free article] [PubMed] [Google Scholar] 243.Pollack A

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Because less of the peptide is likely to be degraded in the stomach during oral studies, researchers may find that different dosing models are required to achieve the same systemic exposure compared to the acetate form

Takakura YR, Hanayama K, Akiyoshi, et al