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The science behind these is mixed
This regulatory history provides more confidence than unregulated peptides offer, though off-label use still requires careful consideration
(The Testosterone Trials TTrials) 3
It has not received approval from Health Canada for therapeutic use, meaning it cannot be prescribed or marketed as a treatment
The single most important distinction: Multi-molecule combination (two peptides, one vial): CagriSema = cagrilintide (amylin analog) + semaglutide (GLP-1 agonist) Multi-target single molecule (one peptide, multiple receptors): Tirzepatide = one molecule activating GLP-1 + GIP receptors (dual agonist) Retatrutide = one molecule activating GLP-1 + GIP + glucagon receptors (triple agonist) So CagriSema is a blend
Day 1: 100-200 mg NAD IV (1-3 hrs) Day 4: 50mg NAD SQ Day 6: 50mg NAD SQ Daily: 250mg NR/NMN in the morning Week 3 We also keep roughly the same routine, though you can ramp up to 500mg NAD IV at this point if you feel you can tolerate it's side effects during infusion
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