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The British Journal of General Practice

Mice lacking the modifier subunit of GCL, have a 60% reduction in glutathione, accompanied by abnormal cortical gamma synchrony, decreased parvalbumin interneurons (PV-IN) and behavioral phenotypes relevant to schizophrenia.(49-51)

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In particular, the intraperitoneal administration of K1K1 resulted in a strong neuroprotective activity on motor neurons in ALS animal models (Vallarola et al., 2020)