The appeal here is, frankly, undeniable
NAC (N-Acetyl Cysteine): A powerful antioxidant precursor that supports glutathione production and may help protect hair follicles from oxidative stress
References 1 Abou-AlfaG
However, the clinical heterogeneity observed in PEM suggests that other pathophysiological systems, such as coagulation cascade abnormalities, autonomic dysfunction, and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, may coexist within the same patient population and potentially interact with the mechanisms outlined in this framework
Regarding CSSS, there was a significant decrease in CSSS in all studied patients after intervention (the range decreased from an initial of 19118 to 1099 after intervention with a P-value of 0.025)
Individuals with higher oxidative stress levels, significant sun exposure history, or hormonal pigmentation may require longer treatment durations